Personal Profile
| Name | Piya Ghosh |
| Designation | SACT |
| Department | Microbiology |
| Email Id | piyapc@gmail.com |
| Year of Joining present service | 2020 |
| Date of Appointment SACT | 01-01-2020 |
Educational Qualifications
| Passout Year | Examination | Passout From | Division |
|---|---|---|---|
| 2019 | Research Associateship | Biophysics Department, Bose Institute (as CSIR-RA from 2017 to 2019) | |
| 2017 | Postdoctoral Research | Biophysics Department, Bose Institute (as Institute Research Associate from 2016 to 2017) | |
| 2016 | Ph.D. | University of Calcutta (Ph.D done under supervision of Prof. Siddhartha Roy, Ex-Director, Indian Institute of Chemical Biology, Kolkata) | |
| 2007 | Master of Science (M.Sc.) | University of Calcutta (M.Sc in Biochemistry) | 1st CLASS |
| 2005 | Bachelor of Science (B.Sc.) | University of Calcutta (Chemistry Honours, Presidency College) | 1st CLASS |
Area of Research and Interest
| Details |
|---|
| Ph.D Research: Development of peptidomimetics (branched dimeric peptides) to inhibit protein-protein interactions in signaling pathways de-regulated in cancer, particularly malignant melanoma cells and to develop and test peptides which specifically target to cancerous tumors and/or blood vessels associated with the tumors in syngenic mouse melanoma model. Post-Doctoral Research: As Extended Senior Research Fellow (Institute) from July, 2015 to January, 2016 and as Research Associate (Institute) from February, 2016 to May, 2017 in Department of Biophysics, Bose Institute on “Development of Synthetic Transcription Factors against pluripotency to Target Cancer Stem Cells” and as CSIR-Reseach Associate from June, 2017 till May, 2019, on “Understanding Molecular Basis of Drug Resistance Induced by Mutant p53” under the supervision of Prof. Siddhartha Roy. Current Area of Research • Assessing biological pollution markers and the effects of climate change in Sundarban Biosphere Reserve by enumeration, isolation and characterization of microorganisms exhibiting bioremedial properties like heavy metal leaching from soil, petroleum degradation and azo-dye degradation in soil under saline stress respectively. • Characterization of proteolytic enzymes from soil microorganisms for application in waste management. |
Publication: Research Papers in Journals
| Sl No. | Year/Month | Title | Name of Journal | Volume / Page No. |
|---|---|---|---|---|
| 1 | 2023 | Study of nano-hydroxyapatite tagged alkaline protease isolated from Himalayan sub-alpine Forest soil bacteria and role in recalcitrant feather waste degradation | International Journal of Biological Macromolecules (Elsevier) | 253, 127317 |
| 2 | 2018 | Mutant and Wild-Type Tumor Suppresor p53 Induces p300 Autoacetylation | iScience (Cell Press) | 2018; 4, 260-272 |
| 3 | 2018 | Constrained alpha-helical peptides as inhibitors of Protein-Protein and Protein-DNA interactions | Biomedicines (MDPI) | 6, 118 |
| 4 | 2018 | A Peptide-based Synthetic Transcription Factor Selectively Activates Transcription in a Mammalian Cell | Chemical Communications (Camb) (Royal Society of Chemistry) | 54, 1611-1614 |
| 5 | 2014 | Simultaneous Inhibition of Key Growth Pathways in Melanoma Cells and Tumor Regression by a Designed Bidentate Constrained Helical Peptide | Peptide Science (Wiley Periodicals, LLC) | 101(4), 344-358 |
| 6 | 2012 | Peptide based Molecules as Protein-Protein Interaction Inhibitors: Tools for Chemical Genetics and Therapy | Current Chemical Biology (Bentham Science Publisher) | 6(2), 145-163 |
Publication: Chapters in books
| Sl No. | Year/Month | Book Title | Chapter Title | Editor/Author | ISBN No. |
|---|---|---|---|---|---|
| 1 | 2021 | Protein–Protein Interaction Regulators (Publisher: Royal Society of Chemistry.) | “Helix-mimetics as Protein–Protein Interaction Inhibitors”, Chapter 7 | Siddhartha Roy and Haian Fu | ISBN (Print) 978-1-78801-187-7 |
Scholarship/Award/Felicitations
| Sl No. | Year/Month | Details of Awards |
|---|---|---|
| 1 | 2017 | CSIR-Research Associateship |